Browsing by Subject "C3 missense mutations, complement system, malaria, severe malaria anemia, incident risk ratio, P. falciparum A"

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    • Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia 

      Evans Raballah, Samuel B Anyona, Qiuying Cheng, Elly O Munde, Ivy-Foo Hurwitz, Clinton Onyango, Caroline Ndege, Nicolas W Hengartner, Maria Andreína Pacheco, Ananias A Escalante, Christophe G Lambert, Collins Ouma, Henri C Jr T Obama, Kristan A Schneider, Philip D Seidenberg, Benjamin H McMahon, Douglas J Perkins (SAGE Publications, 2021)
      Severe malarial anemia (SMA) is a leading cause of childhood morbidity and mortality in holoendemic Plasmodium falciparum transmission regions. To gain enhanced understanding of predisposing factors for SMA, we explored ...