Browsing Biomedical Science by Title
Now showing items 14-33 of 40
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Effect of knockdown resistance on plasmodium falciparum sporozoite rates in malaria vectors in western Kenya
(Maseno University, 2017) -
Effect of maternal plasmodium falciparum malaria infection during pregnancy on trans-placental transfer of Epstein Barr virus-specific igG antibodies, fetal lymphocyte homeostasis and cytokines in Chulaimbo
(Maseno University, 2015)Co-infection with malaria and Epstein Barr virus (EBV) have been implicated in the etiology of endemic Burkitt’s lymphoma (eBL) but the precise mechanism by which these two agents lead to the pathogenesis of eBL has been ... -
Efficacy of Chlorfenapyr and Clothianidin Insecticides on Anopheles Malaria Vector populations of Nyando, Bumula and Ndhiwa sub-counties, Western Kenya
(Maseno University, 2018)Malaria is a global health problem resulting in 435,000 deaths annually with 90% of the deaths occurring in sub-Saharan Africa. Over 70% of the Kenyan population is at risk of malaria and western Kenya is an endemic region ... -
An evaluation of Bacteriological quality of Water from ready-to-eat food outlets in Maseno Township, Western Kenya
(Maseno University, 2016)Water is a commodity which is essential for life as it has long been singled out globally as the most important factor in sustaining human health. Among other factors linked to human health; water has been implicated in ... -
Evaluation of the performance of Sacace HPV genotypes 14 real-tm quant and Carehpv against linear array in detection of human Papilloma virus genotypes in women from Western Kenya
(Maseno University, 2018)Cervical cancer (CC) is common among women, with global estimates of over 530,000 new cases and over 270,000 deaths annually. Human papilloma virus (HPV) infection increases the risk for CC development while high HIV ... -
Evaluation of the Repellency Effectiveness of Linalool and Metofluthrin against Anopheles Gambiae S.L. in Kisian Village, Western Kenya
(Maseno University, 2012)Malaria continues to pose a major public health threat. Despite the efforts that have been made to prevent humans from mosquito bites, changes in the vector biting behavior, and mosquitoes tending to bite earlier before ... -
Expression of cd23 by schistosoma mansoni antigen-activated b cells of highly exposed adult males on the shores of lake Victoria, Western Kenya
(Maseno University, 2016)Increased B cell membrane CD23 (low affinity IgE receptor) and its soluble cleavage product (sCD23) is related to the development of resistance to re-infection with Schistosoma mansoni. CD23 occurs as two isoforms (CD23a ... -
Immunophenotypic Characterization of Lymphocyte Subsets -Expressing Programmed Death-L (Pd-L) in Individuals Exposed to Differential Malaria Transmission Patterns and Endemic Burkitt's Lymphoma
(Maseno University, 2011)Repeated..challenge'of the immune system by chronicexposure to high antigen.levels due to persistent infection may lead to development of impaired T-cells that are not effective in . . . . .' \ mediatingimmune functions. ... -
Influence of cyp2b6 polymorphisms on cd4+ t cell count and HIV RNA viral load changes among individuals on nevirapine Containing highly active antiretroviral therapy
(Maseno University, 2016)Human Immunodeficiency Virus (HIV) remains the leading cause of morbidity and mortality in Kenya with a prevalence of 6.5%. Highly active antiretroviral therapy (HAART) is used to manage the disease by increasing the CD4 ... -
Interaction between shigella flexneri and intestinal epithelial cells co-infected with selected enteric bacteria
(Maseno University, 2015)Bacteria, intestinal epithelium, and host innate immune responses are among the most critical interacting factors that determine the fate of bacterial infections and disease outcomes. Recent studies have described multiple ... -
Isoniazid and Rifampicin Resistance and Patient Treatment Response in a Tuberculosis and Hiv-1 Co-Endemic Population in Western Kenya in 2012-2014
(Maseno University, 2017)In 2015, 10.4 million people worldwide had tuberculosis (TB) and 1.4 million deaths occurred, 400 000 of whom were HIV-positive, Sub-Saharan Africa (SSA) accounted for 81% of these cases. In 2015, 480 000 new cases of ... -
Lack of Association between Interleukin-6 (-174g/C),Interleukin-Io (-1082a/G, -819c/T, And -592c/A) Polymorphisms and Susceptibility to Endemic Burkitt Lymphoma in Children Aged between 5-8 Years from Western Kenya
(Maseno University, 2013)Endemic Burkitt lymphoma (eBL) is the most common paediatric cancer in sub-Saharan Africa and occurs at a high incidence in western Kenya. The tumour has the highest proliferative rate of any other human cancer. Although ... -
Mechanisms Responsible for Insecticide Resistance in Anopheles Gambiae S.L. Populations of AHERO, BUDALANGI and BUNGOMA in Western Kenya
(Maseno University, 2011)As malaria control interventions directed against Anopheles vectors through the distribution of insecticide-treated bednets (ITNs) and application of indoor residual sprays (IRS) increase in sub-SaharanAfrica, it is crucial ... -
Molecular analysis of HIV mutations and determination Of subtypes circulating in gem, western Kenya
(Maseno university, 2010)As the HIV pandemic becomes increasingly complex and devastating in Africa, there is need to come up with better management strategies in terms of treatment, vaccine and better testing methods. However, this is getting ... -
Multiple cytokine responses to mycobacterium tuberculosis antigens in bacille calmette guerrin vaccinated children at Jaramogi Oginga Odinga teaching and referral Hospital in KIsumu county, Western Kenya.
(Maseno University, 2016)The diagnosis and control of tuberculosis (TB) has taken various dimensions with interferon Gamma (IFN-γ) Release Assays (IGRA) currently employed for diagnosis of latent TB infection while the conventional method of ... -
Phenotypic characterization of virulence, evolutionary Relationship and global expansion in Trypanosoma evansi isolates from Surra endemic regions
(Maseno University, 2018)ABSTRACT Trypanosoma evansi parasite is the causative agent of trypanosomiasis (surra) in camels and other livestock with devastating economic consequences in many parts of the world, including Kenya, Vietnam, Brazil, ... -
Plasmodium Falciparum Malaria Transmission Effects on Natural Killer Cell Function in the Etiology of Endemic Burkitt Lymphoma in Children From Western Kenya
(Maseno University, 2016)ABSTRACT The exact etiological mechanism underlying endemic Burkitt lymphoma (eBL) remains unknown. Past studies show T and B cells are immuno-deregulated in children from malaria holoendemic regions. However, no study ... -
Polymorphisms of toll like receptor 4 (-8984c/g and 299asp/gly) and Interferon gamma levels in children with severe Plasmodium Falciparum malaria Anaemia in Siaya county, Western Kenya
(Maseno University, 2018)Plasmodium falciparum (P. falciparum) malaria is a major cause of childhood morbidity and mortality in Sub-Saharan Africa despite the integrated approaches put in place to control the disease. Most of the mortality in ... -
Prevalence and intensity of the common Parasitic infections and Anaemia in street children compaired to school going children in Kisumu city, Kenya.
(Maseno University, 2018)The provision of skilled care during delivery is an indicator to monitor progress in reducing maternal mortality and falls in Goal 3 of the Sustainable Development Goals (SDGs). However, the proportion of Skilled Birth ... -
Prevalence, molecular pathotypes, clinical outcomes and antibiotic profiles of escherichia coli, salmonella and shigella from diarrhoea inpatients aged below five years at Moi Teaching and Referral Hospital
(Maseno University, 2015)Diarrhoea remains a major cause of mortality and morbidity worldwide. Diarrhoea in low income settings is attributed to bacterial enteropathogens but viruses and parasites may also be involved. Children infected with HIV ...