Browsing by Author "Smulski, Cristian R"
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Protein–protein interaction map of the Trypanosoma cruzi ribosomal P protein complex
Ayub, Maximiliano J; Smulski, Cristian R; Nyambega, Benson; Bercovich, Natalia; Masiga, Dan; Vazquez, Martín P; Aguilar, Carlos F; Levin, Mariano J (Elsevier, 2005-09-12)The large subunit of the eukaryotic ribosome possesses a long and protruding stalk formed by the ribosomal P proteins. Four out of five ribosomal P proteins of Trypanosoma cruzi, TcP0, TcP1α, TcP2α, and TcP2β had been ... -
Selective Blockade of Trypanosomatid Protein Synthesis by a Recombinant Antibody Anti-Trypanosoma cruzi P2β Protein
Ayub, Maximiliano J; Nyambega, Benson; Simonetti, Leandro; Duffy, Tomas; Longhi, Silvia A; Gómez, Karina A; Hoebeke, Johan; Levin, Mariano J; Smulski, Cristian R (Public Library of Science, 2012-05-03)The ribosomal P proteins are located on the stalk of the ribosomal large subunit and play a critical role during the elongation step of protein synthesis. The single chain recombinant antibody C5 (scFv C5) directed against ...