Comparison of GeneXpert and line probe assay for detection of Mycobacterium tuberculosis and rifampicin-mono resistance at the National Tuberculosis Reference Laboratory, Kenya
Publication Date
2019-10-15Author
S.A. Aricha, L. Kingwana, N.W. Mwirigi, L. Chaba, T. Kiptai, J. Wahogo, J.S. Otwabe, O.P. Onyango, M. Karanja, C. Ayieko, S.W. Matu
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The dual challenge of low diagnostic sensitivity of microscopy test and technical challenge of performing a TB culture test poses a problem for case detection and initiation of Tuberculosis (TB) second-line treatment. There is thus need for a rapid, reliable and easily accessible assay. This comparative analysis was performed to assess diagnostic performance characteristics of GeneXpert MTB/RIF and Line Probe Assay (LPA).
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