Triterpenes from Elaeodendron schweinfurthianum and Their Antimicrobial Activities against Crop Pathogens
Publication Date
2017-01-26Author
Awino, Sylvia
Arot Manguro, Lawrence Onyango
Owuor, Philip O
Ateka, Elijah M
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Show full item recordAbstract/ Overview
Phytochemical evaluation of Elaeodendron schweinfurthianum (Loes) extracts led to the
isolation of nine compounds which were identified as 3-oxofriedelane (1), 3α-
hydroxyfriedelane (2), 3-oxo-29-hydroxyfriedelane (3), 3-oxofriedelan-28-al (4), α-amyrin
(5), α-amyrin acetate (6), β-sitosterol (7), stigmasterol (8) and lanosterol (9). The structures of
the compounds were determined using spectroscopic and physical methods as well as by
comparison with literature data. The in vitro antimicrobial activities of the extracts and
isolates were investigated against fungi and bacteria which infect food crops. All the crude
extract inhibited the growth of the tested pathogens with EtOAc and n-hexane extracts being
the most active with 11.3 and 7.3 mm diameter zone of inhibition respectively. All the
compound showed antimicrobial activity except compounds 3 which did not exhibit any …
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- Department of Chemistry [326]