School of Medicine: Recent submissions
Now showing items 241-260 of 560
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Influence of changing day secondary into boarding on students’ participation in public secondary schools in Trans Nzoia West, Kenya
(University of Nairobi, 2015)Changing day secondary into boarding schools is an emerging trend in education sector in Kenya. This trend however tends to affect students’ participation in education. This study was conducted in schools that changed from ... -
Intermittent Screening and Treatment or Intermittent Preventive Treatment With Dihydroartemisinin-Piperaquine Versus Intermittent Preventive Treatment With Sulfadoxine …
(LWW, 2016)In sub-Saharan Africa, there are >32 million pregnancies annually. As this is a malaria-endemic region, it is estimated approximately 12 million women who have live births (45% of live births) would be exposed to malaria ... -
Knowledge and Attitude of Agricultural Extension Providers on Use of Agrochemicals in Migori County, Kenya
(2017)Migori County located in South Western Kenya is currently experiencing severe environmental problems as a result of use of various agrochemicals in crop cultivation approaches and cropping methods meant to ensure increased ... -
Intermittent screening and treatment with dihydroartemisinin-piperaquine for the prevention of malaria in pregnancy: implementation feasibility in a routine healthcare system …
(BioMed Central, 2020): Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for preventing malaria in pregnancy in areas of moderate-to-high transmission in sub-Saharan Africa. However, due ... -
Knowledge and adherence to the national guidelines for malaria diagnosis in pregnancy among health-care providers and drug-outlet dispensers in rural Western Kenya
(The American Society of Tropical Medicine and Hygiene, 2018)Prompt diagnosis and effective treatment of acute malaria in pregnancy (MiP) is important for the mother and fetus; data on health-care provider adherence to diagnostic guidelines in pregnancy are limited. From September ... -
A comparative performance of indigenous chicken in Baringo and Kisumu Counties of Kenya for sustainable agriculture
(2016)The population of the world continues to increase especially in developing countries calling for increased food production which puts great pressure to develop a more sustainable agricultural economic activity throughout ... -
Large-scale implementation of disease control programmes: a cost-effectiveness analysis of long-lasting insecticide-treated bed net distribution channels in a malaria-endemic …
(British Medical Journal Publishing Group, 2016)Introduction: Historically, Kenya has used various distribution models for long-lasting insecticide-treated bed nets (LLINs) with variable results in population coverage. The models presently vary widely in scale, target ... -
Pharmacokinetics of mefloquine and its effect on sulfamethoxazole and trimethoprim steady-state blood levels in intermittent preventive treatment (IPTp) of pregnant HIV …
(BioMed Central, 2016)Background Intermittent preventive treatment in pregnancy with sulfadoxine/pyrimethamine is contra-indicated in HIV-positive pregnant women receiving sulfamethoxazole/trimethoprim prophylaxis. Since mefloquine is being ... -
Effectiveness of the delivery of interventions to prevent malaria in pregnancy in Kenya
(BioMed Central, 2016)Background Coverage with malaria in pregnancy interventions remains unacceptably low. Implementation research is needed to identify and quantify the bottlenecks for the delivery and use of these life-saving interventions ... -
A cross-sectional study of the availability and price of anti-malarial medicines and malaria rapid diagnostic tests in private sector retail drug outlets in rural Western Kenya …
(BioMed Central, 2016)Background Although anti-malarial medicines are free in Kenyan public health facilities, patients often seek treatment from private sector retail drug outlets. In mid-2010, the Affordable Medicines Facility-malaria (AMFm) ... -
An assessment of effectiveness of drug rehabilitation programs in Kisii County-Kenya
(Health Education Research & Development, 2016)According to the World Drug Report, approximately 200 million people, about 5% of the World’s population aged between 15 and 64 years have either been forced or voluntarily sought the help of rehabilitation centers for ... -
Community perceptions of mass screening and treatment for malaria in Siaya County, western Kenya
(BioMed Central, 2016)Intermittent mass screening and treatment (iMSaT) is currently being evaluated as a possible additional tool for malaria control and prevention in western Kenya. The literature identifying success and/or barriers to drug ... -
Birth preparedness and complication readiness among women attending antenatal care clinic in health facilities within Bureti sub county of Kericho county, Kenya
(2016)Maternal mortality remains a major public health problem in Kenya with 488 deaths per 100,000 live births. Birth preparedness and complication readiness is one of the recommended strategies by the major global initiatives ... -
User and provider acceptability of intermittent screening and treatment and intermittent preventive treatment with Dihydroartemisinin-Piperaquine to prevent malaria in …
(Public Library of Science, 2016)Background The World Health Organization recommends intermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) alongside long-lasting insecticide-treated nets (LLIN) and case management ... -
Knowledge and adherence to the national guidelines for malaria case management in pregnancy among healthcare providers and drug outlet dispensers in rural, western Kenya
(Public Library of Science, 2016)Background Although prompt, effective treatment is a cornerstone of malaria control, information on provider adherence to malaria in pregnancy (MIP) treatment guidelines is limited. Incorrect or sub-optimal treatment can ... -
Weekly miscarriage rates in a community-based prospective cohort study in rural western Kenya
(British Medical Journal Publishing Group, 2016)Objective: Information on adverse pregnancy outcomes is important to monitor the impact of public health interventions. Miscarriage is a challenging end point to ascertain and there is scarce information on its rate ... -
Dihydrofolate reductase I164L mutations in Plasmodium falciparum isolates: clinical outcome of 14 Kenyan adults infected with parasites harbouring the I164L …
(Royal Society of Tropical Medicine and Hygiene, 2008)Recently, Plasmodium falciparum bearing dihydrofolate reductase (DHFR) I164L was isolated from Africa. Quadruple mutations containing I164L confer high-level resistance to antifolate antimalarials. We prospectively measured ... -
Anna M van Eijk, Peter O Ouma, John Williamson, Feiko O Ter Kuile, Monica Parise, Kephas Otieno, Mary J Hamel, John G Ayisi, Simon Kariuki, Piet A Kager, Laurence Slutsker
(The University of Chicago Press, 2008)Sulfadoxine-pyrimethamine (SP) inhibits folate metabolism by the malaria parasite.We investigated the association between folate levels and SP failure in pregnant women. Data from a trial to assess the effect that folate ... -
Stephanie Dellicour, Meghna Desai, George Aol, Martina Oneko, Peter Ouma, Godfrey Bigogo, Deron C Burton, Robert F Breiman, Mary J Hamel, Laurence Slutsker, Daniel Feikin, Simon Kariuki, Frank Odhiambo, Jayesh Pandit, Kayla F Laserson, Greg Calip, Andy Stergachis, Feiko O Ter Kuile
(BioMed Central, 2015)Background The artemisinin anti-malarials are widely deployed as artemisinin-based combination therapy (ACT). However, they are not recommended for uncomplicated malaria during the first trimester because safety data from ... -
A randomized controlled trial of folate supplementation when treating malaria in pregnancy with sulfadoxine-pyrimethamine
(Public Library of Science, 2006)Objectives: Sulfadoxine-pyrimethamine (SP) is an antimalarial drug that acts on the folate metabolism of the malaria parasite. We investigated whether folate (FA) supplementation in a high or a low dose affects the ...