| dc.description.abstract | Resting metabolic rates have been measured and compared with hepatic 
mitochondrial respiration in Kwashiorkor and diet-induced obese weaned rats. In 
Kwashiorkor, resting metabolic rate was 21% lower than the value of controls, while that of 
the obese rats was 14% higher than in control animals. The resting metabolic rate for 
Kwashiorkor animals was 50% of the predicted basal metabolic rate (BMR), whereas that of 
the obese rats was 23% higher than the predicted BMR. The mitochondrial oxygen 
consumption patterns, using malate plus glutamate or succinate as respiratory substrates, 
revealed that the resting respiration (state 4) was 23.9% higher in Kwashiorkor and 29.1% 
higher in obese animals, while the active (state 3) respiration was 34.8% lower in 
Kwashiorkor and 43.3% lower in obese rats compared to controls. The respiratory control … | en_US |