Effects of Achyranthes aspera, Bidens pilosa and Ajuga remota Leaf extracts on the blood glucose levels and hemoparameters in male goats treated with Alloxan

Abstract

Diabetes mellitus is a potentially morbid condition with high prevalence worldwide thus the disease constitutes a major health concern. Presently, it is an incurable metabolic disorder which affects about 2.8% of the global population. Hyperglycemia brings about many complications in the body including production of changes in blood constituents. This study demonstrated the effect of hyperglycemia on different blood constituents with special emphasis on white blood cell and platelet count and hemoglobin and packed cell volume content as well as its influence on immunological changes on alloxan induced diabetes in the Small East African male goats. The study determined the phytochemicals present in ethanolic extracts of Achyranthes aspera, Bidens pilosa and Ajuga remota and their possible roles in reversing the hemoparameter changes in alloxan-induced diabetic Small East African goats.