Browsing Department of Medical Biochemistry by Issue Date
Now showing items 41-60 of 282
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Prolactin levels in South African women on injectable progestogen contraceptives
(Health and Medical Publishing Group, 1999)To demonstrate the effect of depot medroxyprogesterone acetate (DMPA) and norethisterone oenanthate (NET EN) on basal prolactin levels with a view to investigating the role of progestogen-induced hyperprolactinaemia ... -
Pregnancy in open heart surgical patients at Kenyatta National Hospital.
(East African medical journal, 1999-01-01)In the past, the Kenyatta National Hospital heart unit policy has been to discourage pregnancy among patients following open heart surgery for valve replacement, in view of the adverse effects of warfarin. OBJECTIVE: To ... -
Epstein‐Barr virus in Hodgkin's disease: frequency of a 30‐bp deletion in the latent membrane protein (LMP‐1) oncogene in South African patients
(John Wiley & Sons, Inc., 1999-08-20)In recent years, substantial evidence has accumulated implicating Epstein-Barr virus (EBV) in the pathogenesis of Hodgkin’s disease (HD) and some non-Hodgkin’s lymphomas (Pallesen et al., 1993; Weiss et al., 1989). It has ... -
Epstein‐Barr virus in Hodgkin's disease: frequency of a 30‐bp deletion in the latent membrane protein (LMP‐1) oncogene in South African patients
(John Wiley & Sons, Inc., 1999-08-20)In recent years, substantial evidence has accumulated implicating Epstein-Barr virus (EBV) in the pathogenesis of Hodgkin’s disease (HD) and some non-Hodgkin’s lymphomas (Pallesen et al., 1993; Weiss et al., 1989). It has ... -
Long term valve-related morbidity following open-heart surgery at the Kenyatta National Hospital.
(East African medical journal, 2000)OBJECTIVE: To determine the incidence of valve morbidity associated with post-operative valve patients at the Kenyatta National Hospital, Nairobi. DESIGN: A combined retrospective and prospective study. Restrospective ... -
Biochemical and molecular diagnosis of glutaric aciduria type 1 in a black South African male child: case report
(East African medical journal, 2001)Glutaric aciduria type I (GA-1) is an inborn error of metabolism caused by a deficiency of the mitochondrial enzyme glutaryl-Co enzyme A dehydrogenase. GA-1 is not uncommon amongst Caucasians but to the best of our knowledge, ... -
National Health Laboratory Services in Kenya: challenges for the new millennium
(East African medical journal, 2001-07)I want to begin by expressing my gratitude to the Kenya Association of Clinical Pathologists for inviting me to this meeting and for making it possible for me to share this momentous occasion with friends and colleagues ... -
Leptin and pre-eclampsia in black African parturients
(Elsevier, 2002-11-01)To measure serum concentrations of the hormone leptin during late pregnancy in Black African women with pre-eclampsia, healthy normotensive pregnant women as controls and healthy normotensive non-pregnant women; secondly, ... -
Thirty day mortality and related variables in open heart patients at the Kenyatta National Hospital, Nariobi
(East African medical journal, 2003) -
The effect of different apo (a) isoforms on plasminogen activation in black South African subjects: cardiovascular topics
(Clinics Cardive Publishing, 2003-05-01)The present study evaluates the effect of different apolipoprotein (a)[apo (a)] isoforms on plasminogen activation. -
Serum cystatin C for assessment of glomerular filtration rate in hypertensive disorders of pregnancy
(Taylor & Francis, 2004-01-01)Assessment of renal function is important in the evaluation of the pregnant hypertensive patient. The aim of this study was to evaluate the diagnostic utility of cystatin C as a marker of glomerular filtration rate in ... -
Complement receptor 1 polymorphisms associated with resistance to severe malaria in Kenya
(BioMed Central, 2005)Background: It has been hypothesized that the African alleles Sl2 and McCb of the Swain-Langley (Sl) and McCoy (McC) blood group antigens of the complement receptor 1 (CR1) may confer a survival advantage in the setting ... -
Post Oesophagectomy Leakage at Kenyatta National Hospital–Nairobi-Kenya
(East and Central African Journal of Surgery, 2005)Background: Post oesophagectomy leakage is a common postoperative complication. This present review was aimed at documenting the problem of post-oesophagectomy leakage and associated variables at Kenyatta National Hospital ... -
Duffy Antigen/Receptor for Chemokines (DARC): Is There a Role in Prostate Cancer?.
(science direct, 2005)Introduction: The Duffy blood group antigens function as chemokine receptors and as receptors for several species of malarial parasites. Approximately 70% of African Americans are Duffy negative as a result of a single ... -
The accuracy of urine dipsticks as a screening test for proteinuria in hypertensive disorders of pregnancy
(Taylor & Francis, 2005-01-01)Proteinuria is used as a criterion in the classification system for hypertensive disorders of pregnancy including preeclampsia. The aim of the study was to evaluate the accuracy of dipstick urinalysis in a single voided ... -
Protein–protein interaction map of the Trypanosoma cruzi ribosomal P protein complex
(Elsevier, 2005-09-12)The large subunit of the eukaryotic ribosome possesses a long and protruding stalk formed by the ribosomal P proteins. Four out of five ribosomal P proteins of Trypanosoma cruzi, TcP0, TcP1α, TcP2α, and TcP2β had been ... -
Duffy Antigen/Receptor for Chemokines (DARC): Is There a Role in Prostate Cancer?.
(American Society of Hematology, 2005-11-16)Introduction: The Duffy blood group antigens function as chemokine receptors and as receptors for several species of malarial parasites. Approximately 70% of African Americans are Duffy negative as a result of a single ... -
The effect of abdominal obesity on insulin sensitivity and serum lipid and cytokine concentrations in African women
(Blackwell Publishing Ltd, 2006-05)Studies have shown clear associations of abdominal obesity with lipid and glucose metabolism and cytokine levels in a number of different population groups. However, no such studies have been performed in an African ... -
Hemifacial spasm: case report
(Kenya Medical Association, 2006-07)A 53 year old lady with diabetes mellitus presented with right hemi-facial spasm (HFS). Brain MRI Scan revealed extensive pan-sinusitis and mild bilateral mastoiditis. She responded well to intravenous ceftriaxone therapy ...