Browsing Department of Biomedical Sciences by Title
Now showing items 12-31 of 81
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Changes in the frequencies of Plasmodium falciparum dhps and dhfr drug-resistant mutations in children from Western Kenya from 2005 to 2018: the rise of Pfdhps S436H
(BMC, 2020)Background: Sulfadoxine-pyrimethamine (SP) is the only anti-malarial drug formulation approved for intermittent preventive treatment in pregnancy (IPTp). However, mutations in the Plasmodium falciparum dhfr (Pfdhfr) and ... -
CHAPTER EIGHTEEN A BIORATIONALE FOR CONTROL OF BIOMPHALARIA PFEIFFERI HOST SNAILS, LARVAE OF ANOPHELES GAMBIAE AND SCHISTOSOMA MANSONI
(Cambridge Scholars Publishing, 2019-11-14)Mosquitoes transmit deadly diseases in tropical countries. Despite tremendous efforts towards disease control, the burden is still huge in endemic areas. In 2015, the region was home to 89% of malaria cases and 91% of ... -
Clinical malaria incidence and health seeking pattern in geographically heterogeneous landscape of western Kenya
(BioMed Central, 2022)Malaria remains a public health problem in Kenya despite sustained interventions deployed by the government. One of the major impediments to effective malaria control is a lack of accurate diagnosis and effective treatment. ... -
Coagulation hallmark indicators of menorrhagia in a comparative study between menorrhagic and healthy women attending Bungoma County Referral Hospital in Kenya
(Research Square, 2024-02-13)Despite the significant burden of menorrhagia among women in Western Kenya, it remains unknown whether coagulation disorders are one of the important underlying causes of this condition in the region. This study evaluated ... -
Comparative genomic and phenotypic characterization of invasive non-typhoidal Salmonella isolates from Siaya, Kenya
(PLOS, 2021)Non-typhoidal Salmonella (NTS) is a major global health concern that often causes blood stream infections in areas of the world affected by malnutrition and comorbidities such as HIV and malaria. Developing a strategy to ... -
Comparison of Different Trapping Methods to Collect Malaria Vectors Indoors and Outdoors in Western Kenya
(Research square, 2023-08-31)Enhanced vector surveillance, is one of the 4 pillars of the WHO’s global vector control response (2017–2030). Human landing catches are the gold standard for entomological surveys but are difficult to implement and expose ... -
Compartment-specific bacterial communities in higher termites
(M icroha bitat-specificity of the hindgut microbiota in higher termites, 2013)The higher termite gut is a highly structured habitat and shows the presence of spatially separated compartments. The differences in physicochemical parameters between the compartments, most importantly pH, play an important ... -
Comprehensive Transcriptome and Mutational Profiling of Endemic Burkitt Lymphoma Reveals EBV Type–Specific Differences
(OnlineFirst, 2017)e most common pedi atric cancer in malaria-endemic equatorial Africa and nearly always contains Epstein–Barr virus (EBV), unlike sporadic Burkitt lymphoma (sBL) that occurs with a lower incidence in developed countries. ... -
CRITICAL FACTORS AND CREDIT UPTAKE IN YOUTH ENTERPRISE DEVELOPMENT FUND IN SUNA EAST CONSTITUENCY, MIGORI COUNTY, KENYA
(KENYATTA UNIVERSITY, 2018-11)Youth entrepreneurship in Kenya plays a significant role in enhancing Kenya’s economic development and in reducing youth unemployment. Despite the great significance of entrepreneurship in Kenya, there is a high failure ... -
CRITICAL FACTORS AND CREDIT UPTAKE IN YOUTH ENTERPRISE DEVELOPMENT FUND IN SUNA EAST CONSTITUENCY, MIGORI COUNTY, KENYA
(KENYATTA UNIVERSITY, 2018-11)Youth entrepreneurship in Kenya plays a significant role in enhancing Kenya’s economic development and in reducing youth unemployment. Despite the great significance of entrepreneurship in Kenya, there is a high failure ... -
Determinants of tuberculosis treatment interruption among patients in Vihiga County, Kenya
(PLOS ONE, 2021)Despite robust Tuberculosis (TB) program with effective chemotherapy and high coverage, treatment interruption remains a serious problem. Interrupting TB treatment means that patients remain infectious for longer time ... -
developing and implementing a Pediatric emergency Care Curriculum for Providers at district level Hospitals in sub-saharan africa: a Case study in Kenya
(Frontiers, 2017-12-11)Introduction: Emergency medicine is a relatively new field in sub-Saharan Africa and dedicated training in pediatric emergency care is limited. While guidelines from the African Federation of Emergency Medicine (AFEM) ... -
Development of a Unifying Target and Consensus Indicators for Global Surgical Systems Strengthening: Proposed by the Global Alliance for Surgery, Obstetric, Trauma, and …
(SPRINGER, 2017-10-01)After decades on the margins of primary health care, surgical and anaesthesia care is gaining increasing priority within the global development arena. The 2015 publications of the Disease Control Priorities third edition ... -
The diagnostic accuracy of Th1 (IFN-γ, TNF-α, and IL-2) and Th2 (IL-4, IL-6 and IL-10) cytokines response in AFB microscopy smear negative PTB- HIV co-infected patients
(Springer, 2019)Acid Fast Bacilli (AFB) microscopy smear remains the most widely used laboratory diagnostic technique for Pulmonary Tuberculosis (PTB) in low-and-middle income countries. Although it is highly specifc, the sensitivity ... -
Effects of Achyranthes aspera, Bidens pilosa and Ajuga remota Leaf extracts on the blood glucose levels and hemoparameters in male goats treated with Alloxan
(AJOL, 2021)Diabetes mellitus is a potentially morbid condition with high prevalence worldwide thus the disease constitutes a major health concern. Presently, it is an incurable metabolic disorder which affects about 2.8% of the global ... -
Efficacy of the PermaNet Dual compared to the Interceptor G2 and the PermaNet 3.0 in experimental huts in Siaya County, western Kenya.
(Research Square, 2024-01-25)Pyrethroid-chlorfenapyr nets have shown significant epidemiological impact over pyrethroid-only and pyrethroid plus piperonal-butoxide (PBO) in Africa. Here we describe a non-inferiority evaluation of PermaNet Dual, a ... -
Enzymatic Activity of Endophytic Bacterial Isolates from Selected Mangrove Plants in Kenya
(The Open Microbiology Journal, 2018-11-14)Microorganisms are a preferred source of enzyme production due to their high production capability and low cost of production. Bacterial endophytes occupy unexplored sites hence they represent a new source of enzymes with ... -
Epidemiological patterns and antimicrobial resistance of bacterial diarrhea among children in Nairobi City, Kenya
(RIGLD, Research Institute for Gastroenterology and Liver Diseases, 2020)Aim:Determine the prevalence of enteric bacterial pathogens and their antimicrobial resistance among diarrheic children in Nairobi City, Kenya. Background: Regardless of enteric bacterial pathogens being a major ... -
Evaluating Antiplasmodial and Antimalarial Activities of Soybean (Glycine max) Seed Extracts on P. falciparum Parasite Cultures and P. berghei-Infected Mice
(Hindawi, 2020-02-17)Plasmodium parasite resistance to artemisinin-based combination therapies (ACTs) calls for development of new, affordable, safe, and effective antimalarial drugs. Studies conducted previously on soybean extracts have ... -
Evaluation of cercaricidal and miracicidal activity of selected plant extracts agains larval stages of Schistosoma mansoni
(Journal of Natural Sciences Research, 2016)Schistosomiasis is a parasitic disease caused by blood-flukes of the genus Schistosoma. It is one of the most widespread of all human parasitic diseases, ranking second only to malaria in terms of its socioeconomic and ...