Department of Medical Biochemistry: Recent submissions
Now showing items 161-180 of 282
-
Changes in plasma HDL-cholesterol in women using oral contraceptives in Kenya
(University of Nairobi., 1987)125 black Kenyan women attending the Kenyatta National Family Welfare Clinic were randomly allocated to combined and fixed dose oral contraceptives (Eugynon: 500 mcg dl-norgestrel + 50 mcg ethinyl estradiol or Microgynon: ... -
Characterization of chromosomes with hybrid genes for Hb Lepore-Washington, Hb Lepore-Baltimore, Hb P-Nilotic, and Hb Kenya
(Springer-Verlag, 1987-09-01)This study concerns the characterization of chromosomes with hybrid genes for Hb Lepore-Washington (44 chromosomes), for Hb Lepore-Baltimore (5 chromosomes), for Hb P-Nilotic (8 chromosomes), and for Hb Kenya (7 chromosomes) ... -
beta S-haplotypes and alpha-thalassemia along the coastal belt of Kenya.
(East African medical journal, 1989)In this paper, we present data on studies of beta S-haplotypes and alpha-thalassemia gene in subjects from the indigenous population of the Coast Province of Kenya Of the 7SS patients studied, four were homozygous for beta ... -
Maternal levels of alpha-fetoprotein in African women.
(East African medical journal, 1991-08)In a prospective and cross-sectional study, 147 serum samples from normal antenatal indigenous Kenyan women were analysed for alpha-fetoprotein (AFP) concentrations between 8 and 28 weeks gestation. There was progressive ... -
External quality control performance in clinical chemistry: experience in Kenya.
(East African medical journal, 1993)Analysis of eleven biochemical laboratory tests was done during an International External Quality Assessment Scheme (IEQAS) in which the clinical chemistry laboratory at Kenyatta National Hospital participated. Technicon ... -
Reference intervals for some biochemical parameters in the aged Kenyan population.
(East African Medical Journal,, 1994)Serum levels for sodium, potassium, calcium, inorganic phosphate, urea nitrogen and creatinine were determined in 1101 male and 181 female patients aged 50 years and above. The determinations were carried out on the SMA ... -
Prolactin levels in South African women on injectable progestogen contraceptives
(Health and Medical Publishing Group, 1999)To demonstrate the effect of depot medroxyprogesterone acetate (DMPA) and norethisterone oenanthate (NET EN) on basal prolactin levels with a view to investigating the role of progestogen-induced hyperprolactinaemia ... -
Point mutation (C446S) in the thyroid hormone receptor β gene in a black South African kindred with thyroid hormone resistance syndrome
(1999)Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS/Unless otherwise stated above, the content of this bibliographic record may ... -
GalAactosaemia in black South African children
(Kenya Medical Association, 1999)To evaluate the clinical and biochemical features of all black children confirmed to have galactosaemia from the KwaZulu Natal Province of South Africa. -
Biochemical and molecular diagnosis of glutaric aciduria type 1 in a black South African male child: case report
(East African medical journal, 2001)Glutaric aciduria type I (GA-1) is an inborn error of metabolism caused by a deficiency of the mitochondrial enzyme glutaryl-Co enzyme A dehydrogenase. GA-1 is not uncommon amongst Caucasians but to the best of our knowledge, ... -
Leptin and pre-eclampsia in black African parturients
(Elsevier, 2002-11-01)To measure serum concentrations of the hormone leptin during late pregnancy in Black African women with pre-eclampsia, healthy normotensive pregnant women as controls and healthy normotensive non-pregnant women; secondly, ... -
The effect of different apo (a) isoforms on plasminogen activation in black South African subjects: cardiovascular topics
(Clinics Cardive Publishing, 2003-05-01)The present study evaluates the effect of different apolipoprotein (a)[apo (a)] isoforms on plasminogen activation. -
Serum cystatin C for assessment of glomerular filtration rate in hypertensive disorders of pregnancy
(Taylor & Francis, 2004-01-01)Assessment of renal function is important in the evaluation of the pregnant hypertensive patient. The aim of this study was to evaluate the diagnostic utility of cystatin C as a marker of glomerular filtration rate in ... -
The accuracy of urine dipsticks as a screening test for proteinuria in hypertensive disorders of pregnancy
(Taylor & Francis, 2005-01-01)Proteinuria is used as a criterion in the classification system for hypertensive disorders of pregnancy including preeclampsia. The aim of the study was to evaluate the accuracy of dipstick urinalysis in a single voided ... -
The effect of abdominal obesity on insulin sensitivity and serum lipid and cytokine concentrations in African women
(Blackwell Publishing Ltd, 2006-05)Studies have shown clear associations of abdominal obesity with lipid and glucose metabolism and cytokine levels in a number of different population groups. However, no such studies have been performed in an African ... -
Genetic analysis of HIV-1 subtypes in Nairobi, Kenya
(Public Library of Science, 2008-09-11)Genetic analysis of a viral infection helps in following its spread in a given population, in tracking the routes of infection and, where applicable, in vaccine design. Additionally, sequence analysis of the viral genome ... -
Macro CK in patients with elevated troponin I levels: case report: online article
(Clinics Cardive Publishing, 2012-02-01)CK-MB activity levels can be falsely elevated by the presence of macro CK, especially if immuno-inhibition assays are used in the measurement. In patients with macro CK and cardiac pathology that could result in an elevated ... -
Population-specific evolution of HIV Gag epitopes in genetically diverged patients
(Elsevier, 2013-06-01)Under the host selection pressure HIV evolves rapidly to override crucial steps in the antigen presentation pathway. This allows the virus to escape binding and recognition by cytotoxic T lymphocytes. Selection pressures ... -
HIV-1 progression links with viral genetic variability and subtype, and patient’s HLA type: analysis of a Nairobi-Kenyan cohort
(Springer Berlin Heidelberg, 2014-02-01)In a Nairobi-Kenyan cohort of 50 HIV-1 positive patients, we analysed the prevalence of HIV-1 subtypes and human leucocyte antigen (HLA) alleles. From this cohort, 33 patients were selected for the analysis of HIV-1 infection ... -
Measurement of improvement achieved by participation in international laboratory accreditation in sub-Saharan Africa: the Aga Khan University Hospital Nairobi experience
(Oxford University Press, 2014-02-02)As part of the ISO 15189:2007 accreditation process, the Aga Khan University Hospital Nairobi laboratory became the first internationally accredited hospital laboratory in sub-Saharan Africa outside South Africa in 2011 ...