Browsing by Subject "P. falciparum"

Now showing items 1-2 of 2

Factors associated with non-adherence to Artemisinin-based combination therapy (ACT) to malaria in a rural population from holoendemic region of western Kenya.

Onyango, EO; Ayodo, G; Watsierah, CA; Were, T; Okumu, W; Anyona, SB; Raballah, E; Okoth, JM; Gumo, S; Orinda, GO; Ouma, C (Pub Med Central, 2012-06)

Background Over the years, reports implicate improper anti-malarial use as a major contributor of morbidity and mortality amongst millions of residents in malaria endemic areas, Kenya included. However, there are limited ...
Reduced Systemic Bicyclo-Prostaglandin-E2 and Cyclooxygenase-2 Gene Expression are Associated with Inefficient Erythropoiesis and Enhanced Uptake of Monocytic Hemozoin in Children with Severe Malarial Anemia

Anyona, SB; Kempaiah, P; Raballah, E; Davenport, GC; Were, T; Konah, SN; Vulule, JM; Hittner, JB; Gichuki, CW; Ong’echa, JM; Perkins, DJ (Pub Med Central, 2012-08)

In holoendemic Plasmodium falciparum transmission areas, severe malaria primarily occurs in children <48 mos. and manifests as severe malarial anemia [SMA; hemoglobin (Hb)<6.0 g/dL]. Induction of high levels of prostaglandin-E2 ...