School of Public health & Community Development: Recent submissions
Now showing items 341-360 of 411
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Assessment of palliative care services in western Kenya
(AME, 2017-01)Background: The need for palliative care services is rapidly increasing due to the rising number of patients with non-communicable diseases. The objective of this study was to assess the current availability and barriers ... -
developing and implementing a Pediatric emergency Care Curriculum for Providers at district level Hospitals in sub-saharan africa: a Case study in Kenya
(Frontiers, 2017-12-11)Introduction: Emergency medicine is a relatively new field in sub-Saharan Africa and dedicated training in pediatric emergency care is limited. While guidelines from the African Federation of Emergency Medicine (AFEM) ... -
Prevalence of food insecurity in patients with diabetes in western Kenya.
(Wiley, 2013-06)Aims To determine the characteristics of patients with diabetes who reported food insecurity at three diabetes clinics in western Kenya. Methods This study includes routinely collected demographic data at the first ... -
Reactive case detection of Plasmodium falciparum in western Kenya highlands: effective in identifying additional cases, yet limited effect on transmission
(BioMed Central, 2018-03-13)Background: Identifying asymptomatic reservoirs of malaria parasites using index cases as entry points into the community is potentially a cost-efective way towards achieving malaria elimination. Methods: Within 1 year, ... -
Seroprevalence and determinants of transfusion transmissible infections among voluntary blood donors in Homabay, Kisumu and Siaya counties in western Kenya
(BioMed Central, 2018-03-12)Since the implementation of a series of blood donation safety improvements in Kenya, information about seroprevalence and determinants of transfusion transmissible infections among voluntary blood donors especially in high ... -
Impact of Four Years of Annual Mass Drug Administration on Prevalence and Intensity of Schistosomiasis among Primary and High School Children in Western Kenya: A Repeated Cross-Sectional Study.
(The American journal of tropical medicine and hygiene, 2018-03-12)Schistosomiasis remains a major public health problem in Kenya. The World Health Organization recommends preventive chemotherapy with praziquantel (PZQ) to control morbidity due to schistosomiasis. Morbidity is considered ... -
Barriers and Opportunities to Advancing Women in Leadership Roles in Vector Control: Perspectives from a Stakeholder Survey
(The American journal of tropical medicine and hygiene, 2018-03-19)Increasing the active participation of professional women in vector control (VC) activities may help promote greater gender equity in the workplace and reduce the burden of vector-borne diseases. This stakeholder survey ... -
Assessment of Organizational Factors for Health Management Information System (HMIS) Performance in Elgeiyo Marakwet County, Kenya.
(EPH - International Journal of Medical and Health Science, 2018-03)Health Management Information Systems (HMIS) have been used by many countries using platforms adopted or own-designed. It’s implemented by integrating all healthcare services and gives service providers the ability to ... -
Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults
(Immunogenetics, 2012)Polymorphic variability in immune response genes, such as IL12B, encoding the IL-12p40 subunit is associated with susceptibility to severe malaria in African populations. Since the role of genetic variation in conditioning ... -
Polymorphic Variability in the Interleukin (IL)-1Beta Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL-1Beta Production
(PubMed, 2012)Interleukin (IL)-1beta is a cytokine released as part of the innate immune response to Plasmodium falciparum. Because the role played by IL-1beta polymorphic variability in conditioning the immunopathogenesis of severe ... -
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.
(PubMed, 2012)Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children residing in regions where plasmodium falciparum transmission is holoendemic. Although largely unexplored in children with SMA, ... -
MIF (macrophage migration inhibitory factor) promoter polymorphisms and susceptibility to severe malarial anemia
(Journal of Infectious Diseases, 2012)Severe malarial anemia (SMA) resulting from Plasmodium falciparum infection is one of the leading causes of childhood mortality in sub-Saharan Africa. The innate immune mediator macrophage migration inhibitory factor ... -
Functional Haplotypes of Fc Gamma (Fcy) Receptor (FcyRIIA and FcyRIIB) Predict Risk to Repeated Episodes of Severe Malarial Anaemia and Mortality in Kenyan...
(SN Konah, 2012)Development of protective immunity against Plasmodium falciparum is partially mediated through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variations in human FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ... -
Social and Demographic Characteristics of HIV-Positive Mother-Infant Pair and Their Association with Mother-To-Child Transmission of HIV in Vihiga, Kakamega, Bu...
(2012)The World Health Organization report indicates that in 2013~ 35 million people worldwide lived with HIV and AIDS. Of these, 3.2 million were children age< 15 years. The proportion of women living with HIV has remained ... -
Sputum Smear Conversion Time of HIV Infected and Uninfected Patients with Rifampicin and Isoniazid Mycobacterium tuberculosis gene Mutations in Western Kenya
(2012)Mono-resistant and multi-drug resistant tuberculosis (MDR-TB) has been enhanced by delays in the identification of resistant strains. However, resistance gene patterns and the extent of monoresistant TB and MDR-TB in ... -
The Trends of Progesterone Hormone in Advancing Pregnancy of Human Immunodeficiency Virus-infected Women: A Cohort Study in Western Kenya
(2012)Despite many studies on Human Immunodeficiency Virus (HIV) and pregnancy, there is still insufficient information regarding the effect of HIV on progesterone in advancing pregnancy. In a prospective cohort study, 44 ... -
Upregulation of Peripheral Blood Levels of Immune-Regulatory Interleukin-10 Cytokine in Human Immunodeficiency Virus-infected Compared to Non-infected Pregn...
(2012)Alterations in the cytokine status have been suggested to be at least partly responsible for the immune tolerance during pregnancy. Indeed, interleukin-10 (IL-10) cytokine is known to control inflammationinduced ... -
Polymorphic Variability in the 3'Untranslated Region (UTR) of IL12B is associated with Susceptibility to Severe Anaemia in Kenyan Children with Acute Plasmodium...
(BioMed Central, 2005)Plasmodium falciparum malaria remains a leading cause of morbidity and mortality among African children. Innate immunity provides the first line of defence against P. falciparum infections, particularly in young children ... -
Parasitemia, anemia, and malarial anemia in infants and young children in a rural holoendemic Plasmodium falciparum transmission area.
(American Journal of Tropical Medicine and Hygiene, 2005)Malarial anemia (MA) is a multifactorial disease for which the complex etiological basis is only partially defined. The association of clinical, nutritional, demographic, and socioeconomic factors with parasitemia, ... -
Clinical Predictors of Severe Malarial Anemia in a Holoendemic P. Falciparum Transmission Area
(2005)Severe malarial anaemia (SMA) is a common complication of Plasmodium falciparum infections, resulting in mortality rates that may exceed 30% in paediatric populations residing in holoendemic transmission areas. One ...